Developed by Assessment Technologies, Inc., this network estimates the 10 year likelihood of developing coronary artery disease [CAD],
as a function of accepted coronary disease risk factors.
CAD probabilities generated using the Framingham risk equations as presented in Levy DL, Wilson PWF, Anderson KM,
Castelli WP. Stratifying the patient at risk from coronary disease: new insights from the Framingham Heart Study.
Am Heart J 1990;119:712-7
Smoking Status: Using population values from Modest GA. Cardiovascular risk factors: social determinants of
cardiovascular disease. In: Noble J. Textbook of Primary Care Medicine. Mosby. 1996 pages 148-79.
Total Cholesterol: Based on data in Table 4A: Sytkowski PA, D'Agostino RB, Belanger AJ, Kannel WB. Secular trends in
long-term sustained hypertension, long-term treatment, and cardiovascular mortality. The Framingham Heart Study 1950
to 1990. Circulation 1997;93:697-703.
also:
Johnson CL, Rifkind BM, et al. Declining serum total cholesterol levels among US adults. The National Health and
Nutrition Examination Surveys. JAMA 1993;269:3002-8
HDL Status: Based on data in: Johnson CL, Rifkind BM, et al. Declining serum total cholesterol levels among US adults.
The National Health and Nutrition Examination Surveys. JAMA 1993;269:3002-8.
Systolic Blood Pressure: Derived from data presented in Textor SC. Management of mild hypertension. Mayo Clinic
Proceedings 1989;64:1543-52
Also used data from: Franklin SS, Gustin W, Wong ND, Larson Mg, Weber MA, Kannel WB, Levy D. Hemodynamic patterns
of age-related changes in blood pressure. The Framingham Heart Study. Circulation 1997;96:308-315
Left Ventricular Hypertrophy: Used data from several sources to generate the probabilities:
Graettinger WF, Weber MA. Left ventricular hypertrophy and antihypertensive therapy. Am Fam Phys 1992;46:483-91
also:
Pasty BM, Furberg CD, Kuller LH, et al. Isolated systolic hypertension and subclinical cardiovascular disease in the
elderly. Initial findings from the cardiovascular health study. JAMA 1992;268:1287-91. |